We climb the Tumble as a cyclist or as a runner because we love to cycle and to run. The TumbleUp4Life adds something to that love. It adds the feeling that together we can make a difference. By raising money for cancer research in Wales. That way we can beat cancer sooner.

Why this research is needed

Smiling female scientist holding a pipette and test tubeOver 320,000 people are diagnosed with cancer every year in the UK and more than 17,700 in Wales alone.

Beating cancer needs research that spans the entire country and every new discovery needs to drip down to each town, hospital and cancer patient in South Wales and throughout the UK.

The impact of our work

Cancer Research UK supports numerous local clinical trials in the South Wales, including Aberystwyth, Swansea, Newport, Pontypool and Penarth among others. These trials offer hope to thousands of people with cancer in the region.

We also support the Cardiff Cancer Research UK Centre, a research hub where scientists, doctors and nurses work side by side to speed-up the pace of cancer research even more.

By supporting our work in South Wales you can help us in the fight against cancer. Our research could not progress so efficiently without the dedication of our amazing researchers and supporters in South Wales.

Our research in the capital

As well as being the capital of Wales, Cardiff is set to also become the Welsh capital of cancer research too. It is now home to the Cardiff Cancer Research UK Centre  where our scientists deliver cutting edge research, and also the Cardiff Experimental Cancer Medicine Centre(ECMC) where the latest treatments are revolutionising the way cancer is treated.

Among the strengths of the Cardiff Centre is world-class research into the genes and treatment of bowel and breast cancer and leukaemias. One example is the work of Professor Alan Clarke.

Professor Clarke is studying the genes behind the development of bowel cancer. Knowing how genes interact together is important in helping us understand how bowel cancer starts and develops. This is vital information that could help researchers understand how to  tackle it.

And in the region

Several clinical trials supported by Cancer Research UK through the Wales Cancer Trial Network are ongoing in South Wales’ hospitals, like Dr Tom Crosby’s at the Velindre hospital.

Dr Crosby is looking into an alternative to surgery for people with cancer of the oesophagus(foodpipe) that cannot be removed. He is adding Cetuximab, a biological drug called a monoclonal antibody, to conventional chemotherapy and radiation to see if adding this drug to treatment can help more people survive this type of cancer.

Dr Parker from the Royal Marsden Hospital in Sutton is coordinating another trial, offered in Swansea and Newport. The trial will determine whether or not men should receive radiotherapy straight after surgery for prostate cancer and if radiotherapy works better when hormone therapy is administered at the same time.

At the moment there is no consensus as to how it’s best to treat patients after surgery, and since every treatment comes with side effects, Dr Parker wants to make sure people are not given unnecessary treatment, but that they still get the greatest possible benefits.

The difference you can make

Your support could help us fund essential research and clinical trials that are giving hope and more years to people with cancer across Wales and the rest of the UK.

Please help us by supporting our research in South Wales.